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What
is vitamin D?
Vitamin D, calciferol, is a fat-soluble
vitamin, found in food, but is also produced
in the body after exposure to ultraviolet rays
from the sun. Vitamin D is converted by the
liver and kidney to its active hormone form.
The major biologic function of vitamin D is to
maintain normal blood levels of calcium and
phosphorus. Vitamin D aids in the absorption
of calcium, helping to form and maintain
strong bones. It promotes bone mineralization
in concert with a number of other vitamins,
minerals, and hormones. Without vitamin D,
bones can become thin, brittle, soft, or
misshapen. Vitamin D prevents rickets in
children and osteomalacia in adults, which are
skeletal diseases that result in defects that
weaken bones.
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Vitamin
D sources:
Food
Very few foods naturally contain significant
amounts of vitamin D, including fatty fish and
fish oils. Fortified foods are the major
dietary sources of vitamin D. Prior to the
fortification of milk products in the 1930s, a
bone disease seen in children called rickets
was a major public health problem in the
United States. Milk in the United States is
fortified with 10 micrograms (400 IU) of
vitamin D per quart, and rickets is now
uncommon in the US.
One
cup of vitamin D fortified milk supplies about
one-fourth of the estimated daily need for
this vitamin for adults. Although milk is
fortified with vitamin D, dairy products made
from milk such as cheese, yogurt, and ice
cream are generally not fortified with vitamin
D.
Sunlight
Exposure to sunlight is an important source of
vitamin D. Ultraviolet (UV) rays from sunlight
trigger vitamin D synthesis in the skin.
Season, latitude, time of day, cloud cover,
smog, and sunscreens all affect UV ray
exposure. For example, in Boston the average
amount of sunlight is insufficient to produce
significant vitamin D synthesis in the skin
from November through February. Sunscreens
with a sun protection factor of 8 or greater
will block UV rays that produce vitamin D, but
it is still important to routinely use
sunscreen whenever sun exposure is longer than
10 to 15 minutes. It is especially important
for individuals with limited sun exposure to
include good sources of vitamin D in their
diet.
When
does vitamin D deficiency most often occur?
The most common vitamin D deficiency diseases
are rickets and osteomalacia. Rickets usually
occurs in children, causing skeletal
deformities because the body’s ability to a
utilize calcium is inadequate. Osteomalacia is
an adult vitamin D deficiency disease
resulting in muscular weakness and weak bones.
Vitamin
D deficiency occurs, not only when the dietary
intake of vitamin D is inadequate, but also
when there is limited exposure to sunlight,
when the kidneys cannot convert vitamin D to
its active form, or when there is a
gastrointestinal absorption problem.
In today’s age of vitamin D fortified milk
and other products, this deficiency is more
common in people over 50 years of age rather
than children. As we age the skins’ ability
to convert vitamin D to its active form
decreases and kidneys which help to convert
vitamin D to its active form tend to be less
efficient.
Those
most needing of vitamin D supplementation are
individuals who have limited exposure to
sunlight, people in northern areas, and anyone
who keeps their bodies covered. Also at
greater risk are those with fat malaborption
disease since vitamin D is a fat-soluble
vitamin. Chron’s disease, sprue, cystic
fibrosis, liver disease, pancreatic enzyme
deficiency, and bowel disease may be causes of
fat malabsorption. Also one who has had part
of their stomach removed or stapled for weight
loss is also at risk of fat malaborption
disease.
Supplementation of vitamin D may be necessary
for exclusively breast-fed infants who have
limited exposure to sunlight, since human milk
often does not contain enough vitamin D.
Osteoporosis:
Osteoporosis, a disease of fragile bones,
afflicts at least 25 million adults in the
United States and is one of the primary causes
of bone fractures in the elderly. Having
normal levels of vitamin D in your body helps
keep your bones strong and may help prevent
osteoporosis in elderly, non-ambulatory
individuals, in post-menopausal women, and in
individuals on chronic steroid therapy.
Normal bone is constantly being broken down
and rebuilt. During menopause, the balance
between these two systems is upset, resulting
in more bone being broken down than rebuilt.
Estrogen replacement, which limits symptoms of
menopause, can help slow down the development
of osteoporosis by stimulating the activity of
cells that rebuild bone, but supplementation
is sometimes necessary.
Cancer
and Vitamin D.
Vitamin D may be protective against some
cancers, according to laboratory, animal, and
epidemiological evidence. Some dietary surveys
have associated increased intake of dairy
foods with decreased incidence of colon
cancer. Another dietary survey associated a
higher calcium and vitamin D intake with a
lower incidence of colon cancer. Although a
cancer and vitamin D deficiency link is
suggested, comprehensive research in this area
haven’t yet been conducted to be conclusive.
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Is there a health risk of too much Vitamin D?
Although unlikely, consuming too much vitamin
D can be a health risk. Vitamin D toxicity can
cause nausea, vomiting, poor appetite,
constipation, weakness, and weight loss. It
can also raise blood levels of calcium,
causing mental status changes such as
confusion. High blood levels of calcium also
can cause heart rhythm abnormalities.
Calcinosis, the deposition of calcium and
phosphate in soft tissues like the kidney can
be caused by vitamin D toxicity.
Please
note that this material is intended only as
information and should not be used to replace
the expertise of medical professionals. When
looking for medical help, we believe it best to
consult those who practice not only the more
conventional methods of medicine, but also whose
first consideration are the nutritional
deficiency aspects of disease treatment.
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